Predictive Value of Non-Traditional Lipid Parameters NHHR and the TyG Index for Rapid Kidney Function Decline in Diabetic Patients: A Longitudinal Cohort Study Based on CHARLS
Longitudinal cohort study investigates NHHR and TyG index as predictors of rapid kidney function decline in diabetic patients, suggesting higher risks.
Key Points
This study aims to assess how well NHHR and TyG index can predict rapid kidney function decline in diabetic patients.
Used data from China Health and Retirement Longitudinal Study (CHARLS) 2011–2015.
Analyzed 1051 patients with diabetes focusing on RKFD as the primary endpoint.
Applied logistic regression models, ROC curves, and subgroup analyses to examine associations.
189 individuals (17.98%) developed RKFD during a median follow-up of four years.
Both NHHR and TyG index were positively correlated with RKFD risk, with NHHR showing a more stable predictive ability.
Subgroup analyses revealed stronger predictive value of NHHR in women and non-smokers.