Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 13, 2026

Mulberry leaf supplementation improves glycemic control but not renal or cardiovascular markers in spontaneously hypertensive rats.

View Full Paper
Ask AI
Bookmark
Share

Authors

AGA Gryn-RynkoPMP MuszynskiMJM A Janiak

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates glycemic control effects of mulberry leaf in hypertensive rats, suggesting dietary benefits.

Key Points

  • This study aims to investigate the effects of mulberry leaf supplementation on glycemic control and other health markers in spontaneously hypertensive rats.
  • Male spontaneously hypertensive rats (4 months old, n=10 per group) were assigned to standard chow or chow supplemented with mulberry leaves (7% w/w) for eight weeks.
  • 1-deoxynojirimycin content was quantified using RP-HPLC-DAD.
  • Blood tests assessed glycated hemoglobin and postprandial glucose levels.
  • Mulberry leaf supplementation significantly reduced glycated hemoglobin (HbA1c: 1.98% vs. 2.23%, p=0.021).
  • Postprandial glucose levels at 120 min were lower in the mulberry group (94 mg/dL) compared to control (112 mg/dL, p=0.005).
  • No significant changes were observed in renal, cardiac, or vascular biomarkers or histology.

Cite This Study

Gryn-Rynko et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf5aefaef96ed7f057ab3https://doi.org/10.26402/jpp.2026.2.05
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Mulberry (Morus alba) Leaf Tea on Low-Density Lipoprotein and Malondialdehyde Levels in Dyslipidemic Rats2024
  2. 2Study on active components of mulberry leaf for the prevention and treatment of cardiovascular complications of diabetes2021 · 34 citations
  3. 3The Effect of Mulberry Leaves (Morus alba L) on Blood Pressure and Proteinuria in Rattus Norvegicus Wistar Strain Pre-Eclampsia Model2025
  4. 4A 90‐day preclinical toxicological evaluation in rats of a highly purified and concentrated mulberry leaf extract2024 · 1 citations
  5. 5Mulberry leaf extract exhibits multiple anti-diabetic activities and alleviates dysglycemia, systemic inflammation, hepatic steatosis, and xenobiotic metabolism abnormalities in type 2 diabetic mice2024 · 2 citations