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June 13, 2026Vox Sanguinis

Evolving HIV ‐1 epidemiology, drug resistance and socio‐demographics among blood donors in Dalian, Northeastern China, 2011–2024

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Authors

XDXuelian DengXGXiaohan GuoXLXiaochun Liu

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Overview

Randomized trial assesses HIV-1 infection rates and resistance in blood donors, highlighting the need for enhanced public health strategies.

Key Points

  • This research examines trends in HIV-1 prevalence, drug resistance, and donor characteristics among blood donors in Dalian from 2011 to 2024.
  • Blood donations screened for HIV-1 using antibody, antigen tests, and multiplex nucleic acid testing from 2011 to 2024.
  • Analysis included infection rates, molecular characteristics, drug resistance mutations via the Stanford HIV Drug Resistance Database algorithm.
  • Evaluation of socio-demographic data among blood donors.
  • HIV-1 infection rate peaked at 55.3 per 100,000 donations in 2013, stabilizing at 12-21 per 100,000 recently.
  • Most infected donors were young, male, and first-time donors, with MSM representing 49.8% of infections.
  • 6.8% of HIV-positive samples showed drug resistance mutations, primarily against non-nucleoside reverse transcriptase inhibitors.

Cite This Study

Deng et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf5d7faef96ed7f057bd2https://doi.org/10.1111/vox.70309
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