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June 14, 2026Frontiers in MedicineOpen Access

Choroidal structural and perfusion characteristics across refractive groups in children

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Authors

YLY LiuSecond Affiliated Hospital of Inner Mongolia Medical UniversityGTGetu TaoSecond Affiliated Hospital of Inner Mongolia Medical UniversityYZYifan ZhaoJohn Brown University

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Overview

Retrospective cross-sectional study characterizes choroidal changes in children with varying myopia, suggesting structural insights override perfusion metrics.

Key Points

  • To examine choroidal structural and perfusion characteristics in children with emmetropia and varying degrees of myopia.
  • Retrospective cross-sectional study of 140 children aged 8-14 years
  • Classified into emmetropia, low myopia, and moderate myopia based on cycloplegic SER
  • Used EDI-OCT for structural measurements and OCTA for perfusion analysis
  • Choroidal thickness decreased significantly with increasing myopia severity at all locations
  • No significant differences in OCTA-derived perfusion parameters among groups
  • Structural OCT metrics positively correlated with SER and negatively with AL, while OCTA metrics showed limited correlations

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a2e44a3b1cc60ccdea8a261https://doi.org/10.3389/fmed.2026.1861658
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