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June 14, 2026Frontiers in OncologyOpen Access

Clinical spectrum and treatment of thyroid lymphoma: results of a cohort study of 61 patients

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Authors

SLShuchang LiFirst Affiliated Hospital of Zhengzhou UniversityWGWenjie GuFirst Affiliated Hospital of Zhengzhou UniversityZYZhenzhen YangFirst Affiliated Hospital of Zhengzhou University

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Overview

Cohort study analyzes treatment outcomes in thyroid lymphoma, indicating chemotherapy improves survival.

Key Points

  • This study aims to analyze the clinical spectrum of thyroid lymphoma and explore optimal treatment strategies for improving prognosis.
  • Retrospective cohort study of 61 patients with thyroid lymphoma admitted from 2014 to 2025.
  • Assessment of concurrent Hashimoto's thyroiditis and treatment outcomes, focusing on overall survival and progression-free survival rates.
  • Data collection included histological subtype analysis and risk factor assessment for thyroid diffuse large B-cell lymphoma.
  • Overall survival rates at 1, 3, and 5 years were 85.0%, 78.4%, and 75.6%, respectively.
  • Chemotherapy was associated with improved progression-free survival and overall survival, while surgery alone led to shorter progression-free survival.
  • Independent risk factors for shorter progression-free survival included age ≥60 years and C-myc expression ≥50%.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a2e44a3b1cc60ccdea8a2cchttps://doi.org/10.3389/fonc.2026.1720721
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