What question did this study set out to answer?

The study aims to identify acute physiological parameters at admission that predict the need for invasive mechanical ventilation and in-hospital mortality in geriatric ICU patients.

June 14, 2026CureusOpen Access

Acute Physiological Predictors of Invasive Ventilation and Mortality in Geriatric Intensive Care Unit (ICU) Patients: A Retrospective Cohort Study From India

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The study aims to identify acute physiological parameters at admission that predict the need for invasive mechanical ventilation and in-hospital mortality in geriatric ICU patients.
Conducted a single-center retrospective cohort study of 291 patients aged ≥60 years admitted between June and December 2020.
Extracted admission demographics, comorbidities, physiological, and laboratory parameters from electronic records.
Used multivariable logistic regression for IMV and Cox proportional-hazards modeling for mortality analysis.
Invasive mechanical ventilation required in 42.6% (124 patients); in-hospital mortality rate was 47.1% (137 patients).
Independent predictors of IMV included respiratory rate (aOR 1.05, 95% CI 1.01-1.10) and Glasgow Coma Scale (aOR 0.84, 0.78-0.92).
Lactate was an independent predictor of mortality (aHR 1.22, 1.10-1.36) in patients with measured lactate.

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Implication

Retrospective cohort study identifies key physiological factors predicting ventilation needs and mortality in older ICU patients, suggesting practical assessment methods.

Cite This Study

Jain et al. (2026) studied this question.

synapsesocial.com/papers/6a2e456cb1cc60ccdea8a825 https://doi.org/10.7759/cureus.110695

View Full Paper

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Implication

Retrospective cohort study identifies key physiological factors predicting ventilation needs and mortality in older ICU patients, suggesting practical assessment methods.

Acute Physiological Predictors of Invasive Ventilation and Mortality in Geriatric Intensive Care Unit (ICU) Patients: A Retrospective Cohort Study From India

Key Points

Discussion

Implication

Cite This Study

Acute Physiological Predictors of Invasive Ventilation and Mortality in Geriatric Intensive Care Unit (ICU) Patients: A Retrospective Cohort Study From India

Key Points

Discussion

Implication

Cite This Study

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