Efficacy evaluation of intracervical lymph node immunotherapy (ICLIT) in children with allergic rhinitis and allergic rhinitis complicated with asthma

BACKGROUND: Intracervical lymph node immunotherapy (ICLIT) has demonstrated favorable short-term efficacy and safety in children with allergic rhinitis (AR). However, its efficacy in children with AR complicated by asthma (AR+AA) remain studied. AIMS/OBJECTIVES: To evaluate the validity of ICLIT in children with AR+AA. MATERIAL AND METHODS: Thirty children were enrolled, with 15 in AR group and 15 in AR+AA group. All patients received ICLIT. Total nasal symptom score (TNSS), total ocular symptom score (TOSS), and rhinoconjunctivitis quality of life questionnaire (RQLQ) were assessed at baseline and 3, 6 and 12 months post-treatment. The AR+AA group additionally completed the asthma control questionnaire (ACQ-6) and pediatric asthma quality of life questionnaire (PAQLQ). IgE were measured too. RESULTS: < 0.05). CONCLUSIONS AND SIGNIFICANCE: ICLIT effectively improves symptoms and quality of life in children with both isolated AR and AR+AA.