What is the clinical evidence from this study?

Study design: Case Report. Population: Persistent left-sided superior vena cava requiring pacemaker implantation (n=3). Intervention: Pacemaker implantation. Primary outcome: Procedural success.

What question did this study set out to answer?

To explore the challenges and successes of pacemaker implantation in patients with persistent left-sided superior vena cava (PLSVC).

June 14, 2026JACC Case ReportsOpen Access

Pacemaker Implantation in Persistent Left-Sided Superior Vena Cava

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Key result

Tailored venous access and pacing strategies enable successful pacemaker implantation in persistent left SVC.

Why the study?

Persistent left-sided superior vena cava is a rare congenital anomaly that can make cardiac device implantation challenging and may significantly influence procedural strategy and outcomes.

Population

3 patients with unexpectedly present PLSVC undergoing permanent pacemaker implantation

Design

Case series

Authors

MFMohsin FarooqInterventional Cardiology AHAlaa HamidUniversity of Khartoum AFAzhar FarooquiKettering General Hospital

Discussion

Member takes

Implication

May guide individualized pacing strategies in PLSVC; leaves open prospective evaluation of safety and outcomes.

Key Points

To explore the challenges and successes of pacemaker implantation in patients with persistent left-sided superior vena cava (PLSVC).
Presented a case series of 3 patients with unexpected PLSVC during pacemaker implantation.
Documented procedural adaptations made for each patient based on their specific anatomical challenges.
Utilized modified catheters and guide techniques to facilitate lead placement.
Successful dual-chamber pacemaker implantation in a patient with absent right superior vena cava.
Performed cardiac resynchronization therapy in a patient with severe left ventricular dysfunction using conduction system pacing from the right side.
Achieved successful CRT implantation through left SVC using adapted techniques in a patient with dilated cardiomyopathy.

Study Design

Type

Case Report (n=3)

Structured PICO

Population

3 patients with persistent left-sided superior vena cava who underwent permanent pacemaker implantation.

Intervention

Pacemaker or CRT implantation using tailored procedural strategies (e.g., right-sided approach via left SVC, conduction system pacing, modified catheters)

Outcome

Successful device implantation

Persistent left-sided superior vena cava presents technical challenges during pacemaker implantation, but successful outcomes can be achieved with flexible procedural planning and alternative pacing strategies.

Cite This Study

Farooq et al. (2026) conducted a case report in Persistent left-sided superior vena cava requiring pacemaker implantation (n=3). Pacemaker implantation was evaluated on Procedural success. Pacemaker implantation in patients with persistent left-sided superior vena cava was successfully achieved through flexible procedural planning and alternative venous access and pacing strategies.

synapsesocial.com/papers/6a2e4608b1cc60ccdea8ae4a https://doi.org/10.1016/j.jaccas.2026.108760

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Pacemaker Implantation in Persistent Left-Sided Superior Vena Cava

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Pacemaker Implantation in Persistent Left-Sided Superior Vena Cava

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider