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June 1, 2026Health ExpectationsOpen Access

Model Development on Adherence to Aspirin in Pregnancy: A Co‐Produced Qualitative Systematic Review and Meta‐Ethnography

Raya Vinogradov Eleanor Holden Mehali Patel Rowan Grigg Linda Errington Andy Husband Judith Rankin Vera Araújo‐Soares

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Key Points

The research aims to understand barriers and facilitators affecting low-dose aspirin adherence during pregnancy and to develop a theoretical model for adherence.
Conducted systematic searches on multiple electronic databases without time or language limits.
Utilized a meta-ethnography approach for data synthesis with a focus on co-production involving stakeholders.
Assessed study quality using the Critical Appraisal Skills Programme checklist.
Identified four main constructs with ten sub-themes related to adherence obstacles and supports.
Reported an informational gap and inconsistent health system communication impacting aspirin uptake decisions.
Emphasized the importance of improving information quality for women and their support networks.

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Implication

Systematic review explores barriers to low-dose aspirin adherence in pregnancy, suggesting improvements in information delivery are essential.

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Cite This Study

Vinogradov et al. (2026) studied this question.

synapsesocial.com/papers/6a2e4704b1cc60ccdea8ba65 https://doi.org/10.1111/hex.70703

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Aspirin non-adherence in pregnant women at risk of preeclampsia (ANA): a qualitative studyother · 2021 · 28 citations
2A qualitative study of barriers and facilitators to low‐dose aspirin adherence in pregnancycross-sectional · 2025 · 2 citations
3Adherence to aspirin in the prevention of pregnancy complications: a systematic review2025 · 2 citations
4Lived experiences of women prescribed low-dose aspirin for preeclampsia prevention: a phenomenological studyother · 2026
5Guideline adherence to aspirin prophylaxis use for preeclampsia among healthcare providers in Northwest Ethiopia: an explanatory sequential mixed-methods studyClinical Guideline · 2026 · 1 citations

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Effectiveness of Low-Dose Aspirin (75-150 mg) in Preventing Preeclampsia Among High-Risk Pregnant Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2025

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