Prospective analysis shows significant changes in functional scores before and after stroke diagnosis, indicating critical periods for prevention and management.
Key Points
This analysis aims to understand the long-term trajectories of functional scores before and after stroke diagnosis across different populations.
Analyzed data from four studies: CHARLS, ELSA, HRS, and SHARE with 1325, 754, 3907, and 2902 incident strokes, respectively.
Matched two non-stroke participants by age and gender to each stroke case.
Employed linear mixed models to estimate trajectories of functional scores over time.
Individuals with stroke exhibit a steeper decline in memory, with adjusted β values indicating significant decline across studies.
Stroke participants demonstrate greater limitations in activities of daily living starting several years before diagnosis, increasing for five years post-onset.
Women show greater increases in depressive symptoms (CESD), mobility limitations, and frailty compared to men.