Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 15, 2026BMC AnesthesiologyOpen Access

Effect of PEEP titration on the incidence of elevated driving pressure in laparoscopic bariatric surgery: a randomized superiority trial

View Full Paper
Ask AI
Bookmark
Share

Authors

SSSaullo Queiroz SilveiraSPS x E rgio L. PereiraLSLeopoldo Muniz da Silva

Discussion

Loading...

Member takes

Overview

Randomized trial evaluates PEEP titration effects on driving pressure in obese patients during surgery, indicating potential improved respiratory mechanics.

Key Points

  • This study aims to determine if driving pressure-guided PEEP titration can reduce elevated driving pressure during laparoscopic bariatric surgery in obese patients.
  • Single-center, randomized, superiority trial involving 78 obese patients assigned to three PEEP management groups.
  • Groups included recruitment maneuver followed by driving pressure-guided PEEP, recruitment maneuver with fixed PEEP, and no recruitment maneuver with fixed PEEP.
  • Primary outcome measured was the incidence of driving pressure > 15 cmH₂O during pneumoperitoneum.
  • Driving pressure > 15 cmH₂O occurred in 7.7% of RMTP group during pneumoperitoneum, compared to 46.2% in both RMFP and NRMFP groups (RR 6.00, 95% CI 1.49–24.20; P = 0.01).
  • Post-RM, RMTP maintained a lower incidence of elevated driving pressure (3.8%) compared to RMFP (30.8%; RR 8.00, 95% CI 1.08–59.50; P = 0.04) and NRMFP (46.2%; RR 12.00, 95% CI 1.68–85.73; P = 0.01).
  • No significant differences in secondary outcomes, such as postoperative pulmonary complications, across groups.

Cite This Study

Silveira et al. (2026) studied this question.

synapsesocial.com/papers/6a2f97c8a1cfeec490828c25https://doi.org/10.1186/s12871-026-04026-0
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Individualized positive end-expiratory pressure reduces driving pressure in obese patients during laparoscopic surgery under pneumoperitoneum: a randomized clinical trial2024 · 2 citations
  2. 2Intraoperative Driving Pressure–Guided High PEEP vs Standard Low PEEP for Postoperative Pulmonary Complications2025 · 23 citations
  3. 3Driving pressure guided ventilation in robot-assisted laparoscopic surgery with steep Trendelenburg position: a randomized controlled study2026
  4. 4Driving pressure-guided dynamic PEEP titration reduces atelectasis and improves oxygenation in pediatric laparoscopy: a randomized trial on personalized ventilation strategies2025 · 2 citations
  5. 5Effect of intermittent recruitment manoeuvre combined with PEEP on postoperative atelectasis in obese patients: a randomized controlled trial2026