Umbrella review summarizes evidence on therapeutic interventions' impact on quality of life in individuals with orofacial pain, highlighting varying outcomes.
Key Points
To summarize evidence from reviews and meta-analyses on how therapeutic interventions affect quality of life in neuropathic orofacial pain.
Conducted an umbrella review following Joanna Briggs Institute methodology and PRISMA 2020.
Searched multiple databases for systematic reviews and meta-analyses related to neuropathic orofacial pain until January 2026.
Assessed quality using AMSTAR 2 and ConQual methodologies.
Seven systematic reviews were included with very slight overlap (CCA = 2.14%).
Repetitive transcranial magnetic stimulation improved selected patient-reported outcomes (MD −9.23; 95% CI−11.91 to −6.54).
Microvascular decompression provided sustained pain relief, shown through patient satisfaction and functional recovery.