What is the clinical evidence from this study?

Study design: Other. Population: Development of the rat cerebellum. Intervention: Tropomyosin gene expression. Primary outcome: Expression of tropomyosin genes (alpha, beta, gamma, delta).

September 1, 1990Journal of Neurochemistry

Expression of Tropomyosin Genes During the Development of the Rat Cerebellum

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Key result

During rat cerebellum development, beta- and gamma-tropomyosin genes are not expressed, while delta-tropomyosin produces two mRNAs that peak in the first week and alpha-tropomyosin produces a 3-kb mRNA.

Authors

CFCatherine Faivre‐SarrailhInserm LHLaurence HadCentre National de la Recherche Scientifique CFC. FerrazUniversity Hospital Carl Gustav Carus

Discussion

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Implication

Hypothesis-generating for cytoskeletal roles in rodent cerebellum; leaves open translation to human neurodevelopment or disease.

PICO

Population

Development of the rat cerebellum

Exposure / Comparator

Tropomyosin gene expression

Primary Outcome

Expression of tropomyosin genes (alpha, beta, gamma, delta)

Cite This Study

Faivre‐Sarrailh et al. (1990) studied Development of the rat cerebellum. Tropomyosin gene expression was evaluated on Expression of tropomyosin genes (alpha, beta, gamma, delta). During rat cerebellum development, beta- and gamma-tropomyosin genes are not expressed, while delta-tropomyosin produces two mRNAs that peak in the first week and alpha-tropomyosin produces a 3-kb mRNA.

synapsesocial.com/papers/6a309946912b1f0ec6bcaef1 https://doi.org/10.1111/j.1471-4159.1990.tb04576.x

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Expression of Tropomyosin Genes During the Development of the Rat Cerebellum

Discussion

Member takes

Implication

PICO

Cite This Study

Expression of Tropomyosin Genes During the Development of the Rat Cerebellum

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider