The worst atherogenic index of plasma control was associated with a higher 1-year incidence of hypertension in children and adolescents compared to optimal control (OR 2.43; 95% CI 1.69-3.50; p<0.001).
Cohort (n=12,800)
Yes
Does poor atherogenic index of plasma (AIP) control increase the risk of incident hypertension in Chinese children and adolescents?
Poor control of the atherogenic index of plasma is significantly associated with an increased risk of developing hypertension in children and adolescents.
Odds Ratio: 2.43 (95% CI 1.69–3.5)
p-value: p=<0.001
ABSTRACT The association of atherogenic index of plasma (AIP) control level with hypertension onset in children was still unclear. This study aimed to investigate the association between AIP control levels and risk of childhood hypertension. We obtained data from 12,800 students participating in a national, multi‐center, school‐based health lifestyle intervention program aimed at combating obesity. AIP was calculated using the formula log 10 (TG/HDL‐C), and was categorized into five clusters based on baseline and 1 year follow‐up values. Logistic regression and restricted cubic spline regression models were employed to explore both linear and nonlinear associations between AIP control and hypertension risk. Of the 12,800 students, 830 (6.5%) developed hypertension within 1 year. Compared to the group with optimal AIP control (Class 1), students in Class 4 with poor AIP control ( OR = 1.75; 95% CI: 1.31–2.33; p 0.05). In conclusion, the level of AIP control was associated with the incidence of hypertension in children and adolescents.
Lian et al. (Mon,) conducted a cohort in Hypertension (n=12,800). Poor atherogenic index of plasma (AIP) control vs. Optimal AIP control (Class 1) was evaluated on Incidence of hypertension (OR 2.43, 95% CI 1.69-3.50, p=<0.001). The worst atherogenic index of plasma control was associated with a higher 1-year incidence of hypertension in children and adolescents compared to optimal control (OR 2.43; 95% CI 1.69-3.50; p<0.001).