PET-derived right ventricular strain analysis demonstrated strong correlation with magnetic resonance strain for global longitudinal strain (r=0.77, p<0.0001).
Observational (n=123)
Does PET-derived feature tracking accurately quantify right ventricular strain compared to magnetic resonance imaging?
PET-derived feature tracking is a feasible tool for quantifying right ventricular strain, demonstrating strong correlation with the magnetic resonance reference standard.
Effect estimate: r=0.77
Absolute Event Rate: -24.1% vs -23.4%
p-value: p=<0.0001
UNLABELLED: Positron emission tomography (PET) provides robust assessment of cardiac function, whereas evaluation of the right ventricle (RV) remains challenging. Myocardial strain analysis has emerged as a sensitive marker for subtle wall dysfunction. We aimed to evaluate the feasibility of RV strain quantification using a newly developed PET feature tracking technique, with magnetic resonance (MR) strain as the reference standard. METHODS: Consecutive 123 patients (mean 68 ys, male 101) who underwent rest RESULTS: Mean GLS and GCS were -24.1±6.9% vs. -23.4±5.6% and -16.2±5.4% vs. -16.6±4.2% for PET and CMR, respectively. Both parameters showed strong correlations between the two modalities (r=0.77 and 0.74 for GLS and GCS, respectively; p<0.0001). Bland-Altman analysis demonstrated acceptable agreement, despite the presence of significant proportional bias (GLS: bias 0.1±4.4% limits of agreement (LOA) -8.6 to 8.8, r=0.2, and p=0.01; GCS: bias -0.7±3.6% LOA -7.8 to 6.4, r=-0.4, and p<0.0001, respectively). CONCLUSION: PET derived RV wall strain analysis demonstrated a significant correlation with MR strain. PET feature tracking has the potential as a useful tool to detect RV wall dysfunction in routine clinical practice.
Katahira et al. (Mon,) reported a observational. PET-derived feature tracking vs. Magnetic resonance (MR) strain was evaluated on Global longitudinal strain (GLS) correlation (r=0.77, p=<0.0001). PET-derived right ventricular strain analysis demonstrated strong correlation with magnetic resonance strain for global longitudinal strain (r=0.77, p<0.0001).