Evaluating Knowledge Gaps, Attitudes, and Practices Toward Alzheimer’s Disease: A Community-Based Study in Bisha Province

Background: Alzheimer’s disease is a progressive neurodegenerative disorder and the leading cause of dementia worldwide. Public awareness of its symptoms, risk factors, and management is essential for early detection and appropriate care. This study assessed the knowledge, attitudes, and practices (KAP) regarding Alzheimer’s disease among adults in Bisha Province. Methods: A cross-sectional study was conducted among 403 adults using a structured questionnaire assessing sociodemographic characteristics, knowledge, attitudes, and practices related to Alzheimer’s disease. Descriptive statistics summarized participant responses, while multiple linear regression identified factors associated with knowledge and attitude scores. Results: Of the participants, 52.1% were female, with a median age of 25 years (IQR: 21–45), and most had Bachelor’s/Diploma education (68.7%). Most participants correctly identified amnesia as an early symptom (81.1%), recognized the impact of malnutrition on symptoms (62.8%), and knew patients are prone to depression (58.3%). However, only 16.4% knew the disease cannot be prevented and 32.3% recognized that no cure currently exists. Positive attitudes were common, with most agreeing that patients require continuous monitoring and can still enjoy a good quality of life with proper care. Regarding practices, 83.4% stated they would advise suspected patients to seek medical care. Overall, 42.2% had high knowledge, 42.2% moderate knowledge, and 15.6% low knowledge. Marital status was significantly associated with knowledge scores (B = −0.503, p = 0.032). Conclusion: Adults in Bisha Province demonstrated moderate to high knowledge and positive attitudes toward Alzheimer’s disease; however, notable gaps remain regarding prevention and treatment. Community-based educational programs are recommended to improve awareness and early recognition.