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May 18, 2026Dementia and Geriatric Cognitive Disorders

Alzheimer's prevention knowledge links to better attitudes and practices among middle-aged and elderly individuals.

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Why the study?

The study was conducted to examine the knowledge, attitude, and practice toward Alzheimer's disease prevention among middle-aged and elderly individuals in the community.

Population

1271 middle-aged and elderly individuals visiting Kaifeng Central Hospital

Design

Cross-sectional study

Key result

Among middle-aged and elderly individuals, knowledge about Alzheimer's disease prevention positively influenced both attitude (β=0.625, P<0.001) and practice (β=0.605, P<0.001).

Authors

FWFeiyang WuCYChao YangFWFeifan Wu

Discussion

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Overview

May guide knowledge-focused education on Alzheimer's prevention; hypothesis-generating from cross-sectional data and requires prospective confirmation.

Key Points

  • This study aims to assess knowledge, attitude, and practice toward Alzheimer’s disease prevention among middle-aged and elderly individuals.
  • Cross-sectional design conducted in Kaifeng Central Hospital, China.
  • 1271 individuals completed an investigator-designed KAP questionnaire.
  • Multivariable logistic regression and structural equation modeling were used for analysis.
  • Knowledge scores were low (mean 13.02 ± 5.26), indicating poor understanding.
  • Attitude scores were favorable (mean 38.70 ± 4.42), while practice scores were poor (mean 25.62 ± 3.93).
  • Knowledge positively influenced both attitude (β = 0.625, P < 0.001) and practice (β = 0.605, P < 0.001).

Study Design

Type

Cross-Sectional (n=1,271)

Multicenter

No

Structured PICO

P
Population
1,271 middle-aged and elderly individuals in the community who visited Kaifeng Central Hospital (China), mean age 54.40, 62.71% males.
O
Outcome
Knowledge, attitude, and practice (KAP) scores toward Alzheimer's disease prevention measured by an investigator-designed questionnairepatient reported

Middle-aged and elderly individuals in this Chinese cohort demonstrated poor knowledge and practice but favorable attitudes toward Alzheimer's disease prevention, suggesting that educational interventions could improve preventive practices.

Cite This Study

Wu et al. (2026) conducted a cross-sectional in Alzheimer's disease prevention (n=1,271). Among middle-aged and elderly individuals, knowledge about Alzheimer's disease prevention positively influenced both attitude (β=0.625, P<0.001) and practice (β=0.605, P<0.001).

synapsesocial.com/papers/6a0aad145ba8ef6d83b7099ahttps://doi.org/10.1159/000552507
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