Comparative study evaluates noninvasive chromosomal screening in embryos, suggesting a safer alternative to invasive methods.
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to improve embryo selection in assisted reproductive technology. However, the trophectoderm (TE) biopsy required for testing is invasive and may compromise embryo integrity. Noninvasive chromosomal screening (NICS) using cell-free DNA from spent embryo culture medium (SECM) is a promising alternative.
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温晓君(Wen Xiaojun) (2026) studied this question.
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