Nekroti̇k Enterokoli̇ti̇n Patogenezi̇ndə Və Di̇aqnosti̇kasinda Si̇toki̇nləri̇n Rolu.

Key Points

• The study aims to explore the role of cytokines IL-8 and IL-10 in the pathogenesis and diagnosis of necrotizing enterocolitis.
• Assessed cytokine levels using ELISA method at the Scientific-Research Pediatric Institute's immunology lab.
• Categorized 36 newborns with necrotizing enterocolitis into three groups based on disease stage: suspicion, confirmed, and progressive.
• Used a fully automated analyzer, the Elisys UNO-Human IFA, for accurate cytokine measurement.
• Average IL-8 level in group III was 132.4 ng/l (70.9-202), significantly higher than the control group, which had an average of 14.1 ng/l (10.2-19.5), p<0.001.
• IL-10 levels were similarly elevated in affected groups, indicating a correlation with disease severity.