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June 17, 2026Journal of Neurosurgical Anesthesiology

Anticoagulation and Outcomes After Traumatic Cerebral Venous Sinus Thrombosis: A Retrospective Cohort Study

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Authors

JGJean-Christophe Grondin-HoareauMVMarc VinclairCSClotilde Schilte

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Overview

Retrospective cohort study investigates anticoagulation impact on outcomes in TBI with tCVST, indicating implications for treatment practices.

Key Points

  • This study investigates anticoagulation practices and their effects on outcomes in patients with traumatic cerebral venous sinus thrombosis (tCVST) after traumatic brain injury (TBI).
  • Conducted a retrospective cohort study between 2012 and 2023 in 2 level 1 trauma centers
  • Included TBI patients admitted to intensive care units and extracted data from medical records
  • Used multivariable logistic regression to identify predictors of venous recanalization
  • Among 91 TBI patients with tCVST, anticoagulation practices varied significantly
  • 9.9% of patients experienced new or worsening intracranial hemorrhage under anticoagulation
  • Only tCVST features, such as partial sinus obstruction, were significantly associated with recanalization (OR=7.12, P=0.03)

Cite This Study

Grondin-Hoareau et al. (2026) studied this question.

synapsesocial.com/papers/6a323e06d50b63ecad207643https://doi.org/10.1097/ana.0000000000001125
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical course of traumatic cerebral venous sinus thrombosis: Insights from a UK major trauma centre2026
  2. 2Management and Outcomes of Traumatic Cerebral Venous Sinus Injury Among Patients With Traumatic Brain Injury and Concomitant Intracranial Hemorrhage2026
  3. 3Clinical characteristics, management, and outcomes of traumatic cerebral venous sinus thrombosis2025 · 2 citations
  4. 4Cerebral Venous Thrombosis in Patients With Traumatic Brain Injury: Epidemiology and Outcome2024 · 3 citations
  5. 5Management of Traumatic Cerebral Venous Sinus Thrombosis: A United Kingdom and Ireland Survey on Practice Variation2024 · 1 citations