What question did this study set out to answer?

The aim is to assess the impact of feline leukemia virus on immune function in cats.

Immunologic Reactivity of the Cat: Immunosuppression in Experimental Feline Leukemia

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Randomized trial evaluates immune responses in cats inoculated with feline leukemia virus, indicating significant immunosuppression.

The aim is to assess the impact of feline leukemia virus on immune function in cats.
18 cats inoculated with feline leukemia virus evaluated at 2-week intervals from 5 to 19 weeks of age.
16 age-matched control cats used for comparison.
Assays measured cellular and humoral immune responses including allograft retention times and antibody titers.
16 out of 18 FeLV-infected cats exhibited significantly longer allograft retention times (≥18 days, P<0.01).
Thymic atrophy was noted as early as 5 weeks and persisted through the neoplastic phase.
Humoral antibody responsiveness remained unchanged during leukemogenesis.

Perryman et al. (1972) studied this question.

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