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May 19, 2011Annals of Surgery

Laparoscopy in Combination with Fast Track Multimodal Management is the Best Perioperative Strategy in Patients Undergoing Colonic Surgery

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Authors

MVMalaika S. VlugAmsterdam NeuroscienceJWJan WindAmsterdam NeuroscienceMHMarkus W. HollmannApple (Israel)

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Implication

Randomized trial compares laparoscopic and open surgery with fast track and standard care, indicating best strategies for recovery.

Key Points

  • The aim is to determine the optimal perioperative treatment for segmental resection in colon cancer.
  • Randomized trial across 9 centers with 400 patients undergoing segmental colectomy.
  • Participants were assigned to either laparoscopic or open surgery, and fast track or standard care, creating 4 treatment groups.
  • Primary outcome measured was total postoperative hospital stay, with various secondary outcomes evaluated.
  • Median total postoperative hospital stay was significantly lower in the laparoscopic/FT group at 5 days compared to other groups (P < 0.001).
  • Median postoperative hospital stay was also lower in the laparoscopic/FT group at 5 days, compared to 6 days for the open/FT group and 7 days for the open/standard group (P < 0.001).
  • Regression analysis indicated that laparoscopy was the only independent factor reducing hospital stay and morbidity.

Cite This Study

Vlug et al. (2011) studied this question.

synapsesocial.com/papers/6a327cdbaa3ef5b669e47c02https://doi.org/10.1097/sla.0b013e31821fd1ce
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Prospective Randomized Controlled Trial of Multimodal Perioperative Management Protocol in Patients Undergoing Elective Colorectal Resection for Cancer2007 · 406 citations
  2. 2Gastrointestinal Quality of Life Index: Development, validation and application of a new instrument1995 · 1,312 citations
  3. 3Perioperative strategy in colonic surgery; LA paroscopy and/or FA st track multimodal management versus standard care (LAFA trial)2006 · 179 citations
  4. 4Quality of life and patient satisfaction with enhanced recovery protocols2009 · 93 citations
  5. 5Care after Colonic Operation—Is it Evidence-Based? Results from a Multinational Survey in Europe and the United States2005 · 270 citations