Key result
Plasma soluble thrombomodulin levels were significantly higher in patients with acute ischemic stroke compared to controls (3.08 vs 2.57 ng/mL; P < .005).
Why the study?
Do plasma soluble thrombomodulin (sTM) levels correlate with acute ischemic stroke and its subtypes in Thai patients?
Population
169 Thai individuals, comprising 93 patients with acute ischemic stroke and 76 controls.
Comparison
Measurement of plasma soluble thrombomodulin… vs 76 controls without stroke, and internal…
Design
Case-control
Authors
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May support sTM as acute-phase biomarker; hypothesis-generating for cardioembolic subtype, requires prospective validation.
Case-Control (n=169)
Do plasma soluble thrombomodulin (sTM) levels correlate with acute ischemic stroke and its subtypes in Thai patients?
Absolute Event Rate: 3.08% vs 2.57%
p-value: p=< .005
Plasma soluble thrombomodulin levels are elevated in acute ischemic stroke, particularly in the cardioembolic subtype, suggesting its potential utility as an acute phase biomarker.
Dharmasaroja et al. (2012) conducted a case-control in Acute ischemic stroke (n=169). Acute ischemic stroke vs. Controls was evaluated on Plasma soluble thrombomodulin (sTM) levels (ng/mL) (p=< .005). Plasma soluble thrombomodulin levels were significantly higher in patients with acute ischemic stroke compared to controls (3.08 vs 2.57 ng/mL; P < .005).
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