Key result
Larger epicardial fat volume was independently associated with greater coronary (difference 0.12 per SD increase; 95% CI 0.04-0.19) and extracranial carotid artery calcification in males.
Why the study?
Is epicardial fat volume associated with atherosclerotic calcification in multiple vessel beds?
Population
2298 participants from the population-based Rotterdam Study
Design
Cross-sectional
Authors
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Hypothesis-generating for epicardial fat as systemic atherosclerosis marker in men; prospective studies needed before clinical relevance.
Observational (n=2,298)
Is epicardial fat volume associated with atherosclerotic calcification in multiple vessel beds?
Mean Difference: 0.12 (95% CI 0.04–0.19)
Larger epicardial fat volume is independently associated with greater coronary and extracranial carotid artery calcification in males, suggesting a potential systemic effect on atherosclerosis.
Bos et al. (2015) conducted an observational in Atherosclerotic calcification (n=2,298). Epicardial fat volume was evaluated on Coronary artery calcification volume in males (Difference 0.12, 95% CI 0.04-0.19). Larger epicardial fat volume was independently associated with greater coronary (difference 0.12 per SD increase; 95% CI 0.04-0.19) and extracranial carotid artery calcification in males.
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