Why the study?
Epicardial adipose tissue is suggested to promote coronary plaque development, but whether epicardial fat volume predicts coronary events in the general population was unknown.
Does epicardial adipose tissue (EAT) volume predict incident fatal or nonfatal coronary events in a general population free of baseline cardiovascular disease?
Population
4,093 participants free of cardiovascular disease from the Heinz Nixdorf Recall cohort study
Comparison
Higher vs lower epicardial adipose tissue volume
Design
Prospective population-based cohort study
Follow-up
8.0 ± 1.5 years
Authors
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No current role in routine risk stratification; leaves open whether EAT is a modifiable target for coronary prevention.
Does epicardial adipose tissue (EAT) volume predict incident fatal or nonfatal coronary events in a general population free of baseline cardiovascular disease?
Epicardial fat volume independently predicts incident fatal and nonfatal coronary events in an asymptomatic general population, even after adjusting for traditional risk factors and coronary artery calcification.
Mahabadi et al. (2013) studied this question.
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