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January 1, 2010Heart ViewsOpen Access

Epicardial fat >5 mm was associated with LA enlargement, lower ejection fraction, increased left ventricular mass, and abnormal diastolic function independent of age.

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Why the study?

Is epicardial fat thickness ≥ 5 mm associated with adverse echocardiographic changes and cardiac risk factors in patients undergoing echocardiography?

Population

97 patients undergoing echocardiographic studies (42 females)

Comparison

Epicardial fat ≥ 5 mm (Group I) vs Epicardial fat < 5 mm (Group II)

Design

Cross-sectional

Authors

RGRamil GoelFMFarouk MookadamPJPanupong Jiamsripong

Discussion

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Member takes

Overview

May support epicardial fat as an echo risk marker; hypothesis-generating and should not yet change practice.

Structured PICO

Is epicardial fat thickness ≥ 5 mm associated with adverse echocardiographic changes and cardiac risk factors in patients undergoing echocardiography?

P
Population
97 patients undergoing echocardiographic studies (42 females)
I
Intervention
Epicardial fat ≥ 5 mm (Group I)
C
Comparator
Epicardial fat < 5 mm (Group II)
O
Outcome
Morphologic and physiologic changes on echocardiography (LA enlargement, ejection fraction, LV mass, diastolic function) and cardiac risk factorssurrogate

Echocardiographic epicardial fat >5 mm is a simple, inexpensive marker associated with adverse cardiac structural and functional abnormalities.

Limitations

  • Need for further studies on appropriate cut-off thickness and sites of measurement
  • Need for comparison with other measures of obesity

Cite This Study

Goel et al. (2010) studied this question.

synapsesocial.com/papers/6a7cfea1fdc4b07752aeb422https://doi.org/10.4103/1995-705x.76801
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Different Imaging Modalities in Quantification of Epicardial Adipose Tissue Thickness2014 · 3 citations
  2. 2Association Between Epicardial Adipose Tissue and Cardiac Dysfunction in Subjects with Severe Obesity2023 · 28 citations
  3. 3Association of Epicardial Fat Tissue with Coronary Artery Disease and Left Ventricle Diastolic Function Indicators2018 · 16 citations
  4. 4Increased Epicardial Adipose Tissue Thickness in Type 2 Diabetes Mellitus and Obesity2015 · 79 citations
  5. 5Echocardiographic Epicardial Adipose Tissue as a New Indicator of Cardiovascular Risk2016