Key result
Brachial artery flow-mediated dilation was significantly attenuated in the morning at 8:00 (4.0%) compared to the afternoon at 17:00 (9.7%) (p<0.05).
Why the study?
Does brachial artery flow-mediated dilation exhibit diurnal variation in healthy young men?
Observational (n=13)
Does brachial artery flow-mediated dilation exhibit diurnal variation in healthy young men?
Absolute Event Rate: 4% vs 9.7%
p-value: p=<0.05
Endothelial function, as measured by flow-mediated dilation, exhibits significant diurnal variation and is attenuated in the morning, which may contribute to the morning peak of acute cardiovascular events.
Authors
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Morning FMD attenuation may relate to cardiovascular event timing; leaves open extension to at-risk groups or intervention timing.
Etsuda et al. (1999) conducted an observational in Healthy (n=13). Morning time (8:00) vs. Afternoon time (17:00) was evaluated on Brachial artery flow-mediated dilation (FMD) (p=<0.05). Brachial artery flow-mediated dilation was significantly attenuated in the morning at 8:00 (4.0%) compared to the afternoon at 17:00 (9.7%) (p<0.05).
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