What question did this study set out to answer?

To identify bioactive components in Moringa oleifera seeds and assess their antiaging effects.

Discovery of Potential Antiaging Bioactive Components in the Young Seeds of Moringa oleifera

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To identify bioactive components in Moringa oleifera seeds and assess their antiaging effects.
Utilized UHPLC-Q-TOF-MS for profiling Moringa oleifera pods;
Developed a Python-based pipeline for screening oligopeptides from seeds;
Conducted molecular docking and ROS assays to evaluate antiaging potential.
Nicotinamide riboside was identified in Moringa oleifera for the first time.
Immature-seed oligopeptides, particularly EDEPD, increased SIRT1 activation by 16.44%;
Findings suggest a synergistic effect between NR and oligopeptides on SIRT1 pathways.

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Randomized trial reveals antiaging effects of young seed components in Moringa oleifera, suggesting new dietary therapies.

He et al. (2026) studied this question.

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