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The study aims to assess the antibacterial effects of coconut oil against MRSA both in vitro and in vivo.

In vitro and In vivo antimicrobial effect of coconut oil against Methicillin Resistant Staphylococcus aureus from wound infections

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The study aims to assess the antibacterial effects of coconut oil against MRSA both in vitro and in vivo.
MRSA isolates were obtained from AL-Sadder Teaching Hospital and confirmed via standard methods.
In vitro activity was assessed using the disc diffusion method.
In vivo testing involved treating MRSA-induced skin infections in 24 rabbits with coconut oil, vancomycin, or saline.
Coconut oil produced a 1.5-fold reduction in viable bacterial count compared to the control (P<0.05).
Antibacterial effectiveness was comparable to vancomycin with moderate skin reactions observed.
Coconut oil showed a better zone of inhibition than diluted preparations in vitro.

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Randomized trial evaluates coconut oil’s antibacterial effectiveness against MRSA in rabbits, suggesting alternative treatment options.

Baqer et al. (2023) studied this question.

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