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June 18, 2026Journal of Emergency MedicineOpen Access

In Case You Missed It: Updates in the Evaluation and Management of Pulmonary Embolism in 2025

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Key result

Review supports improved assessment tools, catheter-directed therapies, and mechanical thrombectomy for acute PE.

Why the study?

Acute PE is a major cause of morbidity and mortality, presenting a unique challenge for emergency medicine physicians as research continues to evolve.

Design

Review of 2025 literature

Authors

JGJ. David GatzUniversity of Maryland, BaltimoreKJKevin M. JonesUniversity of GeorgiaCFCheyenne FalatUniversity of Maryland, Baltimore

Discussion

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Implication

May enhance PE care pathways now; leaves open prospective validation of updated tools and therapies.

Key Points

  • Summarize advancements in the evaluation and management of pulmonary embolism based on 2025 literature, focusing on updates relevant to emergency medicine.
  • Reviewed key studies from 2025 on pulmonary embolism evaluation and management.
  • Examined diagnostic tools and treatment options in emergency medicine context.
  • Highlighted findings related to outpatient management and specialized teams.
  • The revised Geneva score shows superior performance in assessing pretest probability.
  • D-dimer testing effectively excludes PE in select high-probability patients.
  • Catheter-directed therapies demonstrate greater efficacy compared to anticoagulation alone.

Structured PICO

P
Population
Patients with acute pulmonary embolism (PE)

This review summarizes 2025 updates in the evaluation and management of acute pulmonary embolism, highlighting advancements in diagnostic tools, risk stratification, and catheter-directed therapies.

Cite This Study

Gatz et al. (2026) conducted a review in Acute pulmonary embolism (PE). Evaluation and management strategies was evaluated. Recent literature supports improved probability assessment tools, imaging strategies, and the value of catheter-directed therapies and large bore mechanical thrombectomy for acute pulmonary embolism.

synapsesocial.com/papers/6a33cfcf14a9c556e6677899https://doi.org/10.1016/j.jemermed.2026.05.040
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Therapeutic Advances in Emergency Cardiology: Acute Pulmonary Embolism2019 · 4 citations
  2. 2Understanding and treating pulmonary embolism in acute settings2024
  3. 3Acute Pulmonary Embolism: Current Concepts in Risk Stratification and Management2026
  4. 4Management of Pulmonary Embolism2016 · 332 citations
  5. 5Pulmonary Embolism: Current Challenges and Future Directions2025 · 1 citations