Key result
Preoperative metabolic syndrome predicted increased all-cause mortality (HR 1.34) and cardiac mortality (HR 2.31) over a 10-year follow-up in non-diabetic patients undergoing coronary artery bypass grafting.
Why the study?
Does preoperative metabolic syndrome increase long-term mortality in patients following coronary artery bypass grafting?
Population
1,183 consecutive patients who had isolated coronary artery bypass grafting at Juntendo University Hospital…
Comparison
Preoperative metabolic syndrome defined by… vs Absence of preoperative metabolic syndrome.
Design
Cohort
Follow-up
mean 10.5±3.6 years
Authors
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May not yet alter post-CABG risk stratification; hypothesis-generating for metabolic interventions in non-diabetics.
Cohort (n=1,183)
No
Does preoperative metabolic syndrome increase long-term mortality in patients following coronary artery bypass grafting?
Hazard Ratio: 1.34 (95% CI 1.03–1.74)
p-value: p=0.028
Preoperative metabolic syndrome is an independent predictor of long-term all-cause and cardiac mortality in non-diabetic patients undergoing coronary artery bypass grafting.
Kajimoto et al. (2008) conducted a cohort in Coronary artery disease requiring isolated CABG (n=1,183). Preoperative Metabolic Syndrome vs. Absence of Metabolic Syndrome was evaluated on All-cause death in non-diabetic patients (HR 1.34, 95% CI 1.03-1.74, p=0.028). Preoperative metabolic syndrome predicted increased all-cause mortality (HR 1.34) and cardiac mortality (HR 2.31) over a 10-year follow-up in non-diabetic patients undergoing coronary artery bypass grafting.