Key result
Metabolic syndrome did not affect early post-operative mortality but was significantly associated with an increased risk of surgical wound infection in CABG patients.
Why the study?
Does metabolic syndrome increase early mortality and morbidity in CABG patients?
Cohort (n=83)
Does metabolic syndrome increase early mortality and morbidity in CABG patients?
In patients undergoing CABG, metabolic syndrome is associated with an increased risk of post-operative surgical wound infections, though it does not appear to impact early mortality.
May warrant enhanced wound surveillance after CABG in metabolic syndrome; leaves open whether interventions reduce infection risk.
Metabolic syndrome is a well-known cardiovascular risk factor closely related to increased insulin resistance. This study assessed the effects of metabolic syndrome on early post-operative mortality and morbidity in 100 coronary artery bypass graft (CABG) patients: 50 patients with and 50 without metabolic syndrome. A total of 17 patients were excluded from the analysis as they did not attend follow-up, leaving 51 males (61.4%) and 32 (38.6%) females of mean +/- SD age 60.02 +/- 9.76 years for analysis. Diabetes, hypertension and a high body mass index were significantly more common in patients with metabolic syndrome. A statistically significant relationship was found between metabolic syndrome and surgical wound infection. Non-significant positive correlations were found between metabolic syndrome and post-operative atrial fibrillation, surgical revision due to haemorrhage, ventricular tachycardia and ventricular fibrillation, and prolonged intubation. In conclusion, metabolic syndrome did not affect mortality, but did increase the risk of post-operative surgical wound infection.
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Özyazıcıoğlu et al. (2010) conducted a cohort in Coronary artery bypass graft (CABG) (n=83). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Early post-operative mortality and morbidity (including surgical wound infection). Metabolic syndrome did not affect early post-operative mortality but was significantly associated with an increased risk of surgical wound infection in CABG patients.
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