Key result
Metabolic syndrome linked to ~18% higher long-term MACCE risk in CAD patients.
Why the study?
The effect of metabolic syndrome on outcomes in patients with preexisting coronary artery disease has not been well studied.
Population
2596 patients with coronary artery disease with complete records from the DESIRE registry
Comparison
Patients with metabolic syndrome vs patients without metabolic syndrome
Design
Cohort study using registry data
Follow-up
Mean 829 days
Authors
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Metabolic syndrome may aid long-term risk stratification in CAD; leaves open whether component-targeted therapy reduces MACCE.
Cohort (n=2,596)
Absolute Event Rate: 11.8% vs 10%
p-value: p=0.044
Hu et al. (2006) conducted a cohort in Coronary artery disease (n=2,596). Metabolic syndrome vs. No metabolic syndrome was evaluated on Major adverse cardiac and cerebral events (MACCE) during followup (p=0.044). Metabolic syndrome in patients with coronary artery disease was associated with a higher rate of long-term major adverse cardiac and cerebral events (11.8% vs 10.0%, P=0.044).