Key result
Phrenic motor neurons serve as the final output of a complex neural network that activates diaphragm muscle fibers to control breathing and expulsive behaviors.
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Design
Review
Reinforces models of respiratory motor output; leaves open therapeutic targeting of phrenic neurons.
Breathing occurs without thought but is controlled by a complex neural network with a final output of phrenic motor neurons activating diaphragm muscle fibers (i.e., motor units). This review considers diaphragm motor unit organization and how they are controlled during breathing as well as during expulsive behaviors.
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Fogarty et al. (2018) studied this question. Phrenic motor neurons serve as the final output of a complex neural network that activates diaphragm muscle fibers to control breathing and expulsive behaviors.
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