Key result
Porcine bioprosthetic valves in children had a 94% failure rate within six years, with catastrophic hemodynamic deterioration often requiring emergency replacement.
Why the study?
What is the failure rate and clinical outcome of left-sided porcine bioprosthetic valves in children?
Cohort (n=17)
What is the failure rate and clinical outcome of left-sided porcine bioprosthetic valves in children?
Porcine bioprosthetic valves in left-sided positions in children have an unacceptably high failure rate (94% within 6 years) due to rapid calcification, leading to a strong recommendation against their use in this population.
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High early failure with porcine valves in children warrants caution in similar cases; leaves open durability of contemporary bioprostheses in pediatrics.
Gary S. Kopf (1986) conducted a cohort in Left-sided cardiac valve disease (n=17). Porcine bioprosthetic valves was evaluated on Bioprosthetic valve failure requiring replacement. Porcine bioprosthetic valves in children had a 94% failure rate within six years, with catastrophic hemodynamic deterioration often requiring emergency replacement.
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