What question did this study set out to answer?

This study investigates how preoperative haemoglobin levels affect the need for blood transfusion in females undergoing cardiac surgery.

June 19, 2026Vox Sanguinis

Marginal anaemia and perioperative transfusion in female patients undergoing cardiac surgery

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Authors

MȘMihai ȘtefanCarol Davila University of Medicine and Pharmacy DFDaniela FilipescuCarol Davila University of Medicine and Pharmacy CPCornelia PredoiCarol Davila University of Medicine and Pharmacy

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Implication

Retrospective analysis shows marginal anaemia increases transfusion risk in females undergoing cardiac surgery, suggesting updated Hb thresholds are needed.

Key Points

This study investigates how preoperative haemoglobin levels affect the need for blood transfusion in females undergoing cardiac surgery.
Conducted a retrospective analysis of 1174 cardiac surgery patients, including 399 females.
Stratified females into groups based on haemoglobin levels: ≥13 g/dL, 12-13 g/dL, and <12 g/dL.
Evaluated predictors of packed red blood cell transfusion using multivariable logistic regression and assessed model performance with ROC analysis.
Transfusion rates were 57.3% for Hb ≥13 g/dL, 69.6% for 12.0-12.9 g/dL, and 87.0% for <12 g/dL (p <0.001).
Females with marginal anaemia received more PRBC units than non-anaemic females and males in the same Hb range.
Marginal anaemia (OR 2.05; 95% CI: 1.39-3.03) and overt anaemia (OR 6.33; 95% CI: 4.40-9.97) were independent predictors of transfusion.

Cite This Study

Ștefan et al. (2026) studied this question.

synapsesocial.com/papers/6a34dd1d65a5b0777af2cf51 https://doi.org/10.1111/vox.70315

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Implication

Retrospective analysis shows marginal anaemia increases transfusion risk in females undergoing cardiac surgery, suggesting updated Hb thresholds are needed.

Marginal anaemia and perioperative transfusion in female patients undergoing cardiac surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

Marginal anaemia and perioperative transfusion in female patients undergoing cardiac surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

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