What question did this study set out to answer?

This study aims to detail the clinicopathological features, treatment approaches, and patient outcomes of oral melanoma cases in South America.

June 19, 2026Head and Neck PathologyOpen Access

Oral Melanoma: A South American Collaborative Series of 21 Cases

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Authors

JAJosé Alcides Almeida de Arruda MVMariana Villarroel‐Dorrego CVClaudia Patricia Peña Vega

Discussion

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Overview

Collaborative retrospective study describes oral melanoma profiles, management, and outcomes in South America, highlighting early recognition importance.

Key Points

This study aims to detail the clinicopathological features, treatment approaches, and patient outcomes of oral melanoma cases in South America.
Collaborative retrospective study including 21 cases diagnosed between 2003 and 2025.
Cases were collected from five oral pathology and oral medicine centers across Argentina, Venezuela, Colombia, and Brazil.
Descriptive analysis of clinicopathological data and treatment outcomes was performed.
Twenty-one oral melanoma cases were analyzed, with a mean age of 63 years and a slight female predominance (52.4%).
Most lesions were asymptomatic at diagnosis (78.3%) and primarily affected the palate/maxillary gingiva (66.7%).
During follow-up, 52.6% of patients died, underscoring the poor prognosis associated with this condition.

Cite This Study

Arruda et al. (2026) studied this question.

synapsesocial.com/papers/6a34dd8765a5b0777af2d30f https://doi.org/10.1007/s12105-026-01936-w

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June 19, 2026Head and Neck PathologyOpen Access

Oral Melanoma: A South American Collaborative Series of 21 Cases

View Full Paper

Ask AI

Bookmark

Authors

JAJosé Alcides Almeida de Arruda MVMariana Villarroel‐Dorrego CVClaudia Patricia Peña Vega

Discussion

Member takes

Overview

Collaborative retrospective study describes oral melanoma profiles, management, and outcomes in South America, highlighting early recognition importance.

Key Points

This study aims to detail the clinicopathological features, treatment approaches, and patient outcomes of oral melanoma cases in South America.
Collaborative retrospective study including 21 cases diagnosed between 2003 and 2025.
Cases were collected from five oral pathology and oral medicine centers across Argentina, Venezuela, Colombia, and Brazil.
Descriptive analysis of clinicopathological data and treatment outcomes was performed.
Twenty-one oral melanoma cases were analyzed, with a mean age of 63 years and a slight female predominance (52.4%).
Most lesions were asymptomatic at diagnosis (78.3%) and primarily affected the palate/maxillary gingiva (66.7%).
During follow-up, 52.6% of patients died, underscoring the poor prognosis associated with this condition.

Cite This Study

Arruda et al. (2026) studied this question.

synapsesocial.com/papers/6a34dd8765a5b0777af2d30f https://doi.org/10.1007/s12105-026-01936-w

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