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June 19, 2026Transboundary and Emerging DiseasesOpen Access

Emergence of Transferable Plasmid Coharboring mcr-1.1 and bla CTX-M−55 Genes in Multidrug‐Resistant Escherichia coli From Mink

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Authors

ZLZizhu LinTianjin Agricultural UniversityWGWeiqi GuoShanghai Veterinary Research InstituteJHJiangang HuShanghai Veterinary Research Institute

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Overview

Randomized trial reveals transferable antimicrobial resistance in Escherichia coli from mink, indicating potential gene transmission risks.

Key Points

  • The research aims to investigate the antimicrobial resistance characteristics of E. coli from mink and identify genomic features associated with multidrug resistance.
  • Isolated MDR E. coli strain EC0D1 from mink lung tissue
  • Conducted antimicrobial susceptibility testing
  • Performed whole genome sequencing and phylogenetic analysis on EC0D1
  • EC0D1 showed resistance to multiple antimicrobial classes, including β‐lactams and fluoroquinolones.
  • Plasmids pEC0D1‐2 and pEC0D1‐3 coharbored mcr-1.1 and bla CTX-M−55, linked to the MDR phenotype.
  • Conjugation assays confirmed the transferability of resistance plasmids between different bacterial recipients.

Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/6a34dd8765a5b0777af2d33chttps://doi.org/10.1155/tbed/4811804
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