Finite element analysis explores ablation depth and optical zone as key determinants of intraocular pressure reduction after refractive surgery

BACKGROUND: keratomileusis (FS-LASIK)-induced geometric alterations of the cornea affect IOP measurements obtained with the Goldmann applanation tonometer (GAT). METHODS: ). IOP values were calculated based on the principle of the GAT, and FE simulation results were compared with clinical IOP data measured using the GAT to validate the model. RESULTS: Clinical data from GAT measurements demonstrated a consistent decrease in IOP following surgery. FE results indicated that the postoperative IOP, ranging from 8.26 mmHg to 13.04 mmHg, decreased by 23%-51% compared to the preoperative IOP of 17.04 mmHg. Deeper ablation depths and larger optical zone diameters were associated with lower postoperative IOP. CONCLUSION: The FE analysis demonstrated a decreasing trend in postoperative IOP with increasing ablation depth and optical zone diameter. These findings provide valuable insights for guiding postoperative IOP monitoring, optimizing surgical parameters, and understanding postoperative corneal biomechanical behavior.