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June 19, 2026Mutagenesis

Nutritional maternal factors affect the frequency of DNA damage in newborns

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Authors

AAAnny Cristine de AraújoFMFabrícia de Medeiros MoraisDADaline Fernandes de Souza Araújo

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Overview

Cross-sectional study investigates maternal nutrition's influence on DNA damage in newborns, suggesting implications for fetal health.

Key Points

  • This study aims to explore how maternal nutritional factors impact DNA damage biomarkers in newborns and mothers.
  • Conducted a cross-sectional study with 209 pregnant women in Northeast Brazil during their third trimester.
  • Collected sociodemographic, lifestyle, and dietary data using a 76-item Food Frequency Questionnaire.
  • Performed micronucleus cytome assays on oral mucosa cells to assess DNA damage.
  • 44.5% of participants had adequate pre-pregnancy nutrition, with a 9.5% rise in low birth weight.
  • Infants of mothers with inadequate nutrition (Clusters 1 and 2) had more DNA abnormalities than those from Cluster 3.
  • Maternal nutritional inadequacy correlated with higher DNA damage in newborns.

Cite This Study

Araújo et al. (2026) studied this question.

synapsesocial.com/papers/6a34de1265a5b0777af2d9c2https://doi.org/10.1093/mutage/geag023
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