Comparative evaluation of antibacterial property of microsutures coated with nanocurcumin and povidone iodine: An in-vitro study

Objectives: This study aimed to compare the antibacterial efficacy of 7-0 polypropylene microsutures coated with nanocurcumin and povidone iodine against Porphyromonas gingivalis in vitro. Methods: Polypropylene microsutures were coated with nanocurcumin using a slurry dipping technique and with povidone iodine using a dip-coating method. Antibacterial activity was assessed on Brucella blood agar using the agar well diffusion method. Porphyromonas gingivalis cultures were inoculated, and zones of inhibition were measured after 48 hours of incubation. Tetracycline was used as the positive control for comparison. Results: Both nanocurcumin- and povidone iodine-coated sutures exhibited antibacterial activity against P. gingivalis . Povidone iodine-coated sutures demonstrated a larger zone of inhibition (3 mm) compared to nanocurcumin-coated sutures (2 mm), indicating relatively higher antibacterial efficacy. Conclusions: Coating microsutures with antimicrobial agents such as nanocurcumin and povidone iodine effectively reduces bacterial growth. Povidone iodine showed slightly superior antibacterial activity compared to nanocurcumin. These findings suggest that antibacterial-coated sutures may help reduce surgical site infections and improve healing outcomes, although further in vivo studies are required to establish long-term clinical effectiveness.