Key result
Obesity was associated with a significantly lower risk of post-hemodialysis hypertension compared to normal weight (OR 0.63; 95% CI 0.40-0.97; P=0.038).
Why the study?
To investigate the hypothesized reverse epidemiology in the relationship between body mass index and blood pressure in hemodialysis patients.
Does higher body mass index reduce blood pressure in patients undergoing chronic hemodialysis?
Cross-Sectional (n=525)
Yes
Does higher body mass index reduce blood pressure in patients undergoing chronic hemodialysis?
Odds Ratio: 0.63 (95% CI 0.4–0.97)
p-value: p=0.038
This study supports the 'reverse epidemiology' hypothesis, showing that higher body mass index is inversely associated with blood pressure in patients undergoing chronic hemodialysis.
Higher BMI linked to lower post-HD hypertension odds; supports reverse epidemiology but hypothesis-generating and should not change practice.
In the general population, obesity is positively correlated with hypertension. On the other hand, there was hypothesis of "reverse epidemiology" in the relationship between body mass index (BMI) and blood pressure (BP) of hemodialysis (HD) patients. This study aimed to investigate the "reverse epidemiology" of the relationship between the two variables in Jakarta, Indonesia. Cross-sectional study was conducted at Cipto Mangunkusumo Hospital, Koja District Hospital, and Cengkareng District Hospital in July 2018. Total sampling was performed with a total of 525 HD patients aged >18 years. All data were analyzed from the medical records. Of 525 patients, 27.4% were obese. The post hoc analyses showed that obese patients had significantly lower post-HD systolic BP (P = 0.006) and diastolic BP (P = 0.004) than the normal-weight patients. The Chi-square analyses showed that the overweight group [odds ratio (OR) = 0.53; 95% confidence interval (CI) 0.31-0.87; P = 0.011] and the obese group (OR = 0. 63; 95% CI 0.400.97; P= 0.038) had significant protective effect (OR <1) on the post-HD hypertension. Being obese was a strong predictor for reduced BP (coefficient β = -0.02; P = 0.031). BMI is inversely associated with BP in patients undergoing chronic HD.
No takes yet. Share an insight, caveat, or question.
Bawazir et al. (2020) conducted a cross-sectional in chronic hemodialysis (n=525). Obesity vs. Normal weight was evaluated on post-hemodialysis hypertension (OR 0.63, 95% CI 0.40-0.97, p=0.038). Obesity was associated with a significantly lower risk of post-hemodialysis hypertension compared to normal weight (OR 0.63; 95% CI 0.40-0.97; P=0.038).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: