Key result
A novel goose astrovirus (GoAstV-SDHZ) was isolated from laying hens with nephritis, sharing 97.2-99.9% nucleotide identity with representative GoAstV2 strains.
This study provides the first evidence of Goose astrovirus genotype 2 infection in Chinese laying hens, highlighting a potential new threat to the poultry industry.
Novel detection in laying hens suggests wider GoAstV host range; leaves open need for poultry surveillance.
Goose astrovirus genotype 2 (GoAstV2), as a contagious pathogen of fatal visceral gout in goslings, has been widely distributed in major goose-producing regions in China since 2017, leading to significant economic losses to the Chinese goose industry. In this study, a novel goose astrovirus (GoAstV-SDHZ) was isolated and identified from laying hens with nephritis for the first time. Phylogenetic analysis of the sequenced genome of ORF2 gene revealed that the GoAstV-SDHZ strain clustered into Group 2 GoAstVs and shared the highest identity with the other representative GoAstV2 in the nucleotide (ORF1a: 97.2-99.7%; ORF1b: 98.4-99.8%; ORF2: 97.2-99.9%) and amino acid sequence (ORF1a: 98.2-100%; ORF1b: 98.8-99.6%; ORF2: 97.4-99.6%). In summary, this study provides the first evidence of the GoAstV2 infection in Chinese laying hens, which raises potential threat to the poultry industry in China.
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Wei et al. (2023) studied Nephritis. Goose astrovirus genotype 2 (GoAstV-SDHZ) infection was evaluated on Isolation and phylogenetic analysis of GoAstV-SDHZ. A novel goose astrovirus (GoAstV-SDHZ) was isolated from laying hens with nephritis, sharing 97.2-99.9% nucleotide identity with representative GoAstV2 strains.
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