Why the study?
To investigate the effect of host age on the outcome of novel goose-origin astrovirus infection.
Population
200 1-day-old healthy goslings
Comparison
Experimental infection at 1 vs 5 vs 15 vs 25 vs 35 D of age
Design
Experimental infection study
Follow-up
15 D after inoculation
Authors
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Infection highly pathogenic at 1–15 days but mild later; leaves open age-targeted prevention strategies for endemic goose farms.
The pathogenicity of the novel goose-origin astrovirus AStV-SDPY in goslings is highly age-dependent, with younger birds being significantly more susceptible to severe disease.
An et al. (2020) studied this question.
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