The BHK-21 An73 cell line yields significantly higher infective titers and 146S virus particles for FMD virus serotypes O, A, and Asia-1 compared to the An30 cell line, making it more suitable for vaccine production.
Supports optimized BHK-21 selection for higher-yield FMD vaccines; leaves open need for scaled validation before production adoption.
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Gülyaz et al. (2021) studied this question.
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