Key result
Obesity was independently associated with an increased risk of postoperative arrhythmias compared to nonobese patients (29% vs 5.6%; OR 4.2; 95% CI 1.7-40; P<0.01).
Why the study?
Does obesity increase postoperative morbidity in adults with congenital heart disease undergoing pulmonary valve replacement?
Cohort (n=71)
Does obesity increase postoperative morbidity in adults with congenital heart disease undergoing pulmonary valve replacement?
Odds Ratio: 4.2 (95% CI 1.7–40)
Absolute Event Rate: 29% vs 5.6%
p-value: p=<0.01
In adults with congenital heart disease undergoing pulmonary valve replacement, obesity is significantly associated with prolonged hospital stays and a higher risk of postoperative arrhythmias.
Obesity may increase arrhythmia risk after PVR in ACHD; hypothesis-generating, prospective studies needed before changing practice.
OBJECTIVE: The impact of obesity on surgical morbidity in adults with congenital heart disease is currently unknown. The aim of our study was to investigate the impact of obesity on postoperative outcomes in adults with congenital heart disease undergoing reoperation for pulmonary valve replacement. METHODS: A retrospective analysis was performed assessing the influence of obesity on surgical outcomes. Obesity was defined as a body mass index ≥30 kg/m2. RESULTS: The mean body mass index of the cohort was 25.9 ± 6.9 kg/m2 . The cohort included 71 patients with 17 patients (24%) being obese. There was no postoperative mortality. Obese patients had a longer hospital length of stay (6.6 vs. 4.7 days; P < .001) and increased incidence of postoperative arrhythmias (29% vs. 5.6%; P = .003) compared with nonobese patients. Multivariable analysis performed using logistic regression with backwards elimination demonstrated obesity was independently associated with hospital length of stay >5 days (odds ratio [OR] = 5.2; 95% confidence interval [CI]: 1.5-18.2, P = .01) and with increased postoperative arrhythmias (OR = 4.2; 95% CI: 1.7-40, P < .01). CONCLUSIONS: Obesity is associated with increased morbidity in adults with congenital heart disease undergoing pulmonary valve replacement, including longer hospitalization and higher risk for postoperative arrhythmias.
No takes yet. Share an insight, caveat, or question.
Buelow et al. (2015) conducted a cohort in Congenital heart disease requiring pulmonary valve replacement (n=71). Obesity (BMI ≥30 kg/m2) vs. Nonobese patients was evaluated on Postoperative arrhythmias (OR 4.2, 95% CI 1.7-40, p=<0.01). Obesity was independently associated with an increased risk of postoperative arrhythmias compared to nonobese patients (29% vs 5.6%; OR 4.2; 95% CI 1.7-40; P<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: