Key result
Exercise training prevented the deterioration in the gain and time delay of arterial baroreflex control of muscle sympathetic nerve activity in patients with chronic heart failure.
Why the study?
Does exercise training improve the gain and reduce the time delay of arterial baroreflex control of muscle sympathetic nerve activity in chronic heart failure patients?
Population
26 chronic heart failure outpatients, age 30-70 years, NYHA Functional Class II-III, LVEF ≤ 40%, and peak…
Comparison
Exercise training on a cycle ergometer at… vs Untrained control group instructed to avoid any…
Design
RCT, Patients were randomized to untrained or exercise-trained groups., Muscle…
Follow-up
16 weeks
Authors
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Supports exercise training to preserve baroreflex control in chronic HF; extends RCT evidence on autonomic benefits.
RCT (n=26)
Open-label
Randomized
No
Does exercise training improve the gain and reduce the time delay of arterial baroreflex control of muscle sympathetic nerve activity in chronic heart failure patients?
p-value: p=<0.05
Exercise training prevents the progressive deterioration of arterial baroreflex control of muscle sympathetic nerve activity in patients with chronic heart failure.
Groehs et al. (2015) conducted an RCT in Chronic heart failure (n=26). Exercise training vs. Untrained control was evaluated on Gain of arterial baroreflex control of muscle sympathetic nerve activity (ABRMSNA) (p=<0.05). Exercise training prevented the deterioration in the gain and time delay of arterial baroreflex control of muscle sympathetic nerve activity in patients with chronic heart failure.
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