Key result
Male sex was associated with a significantly greater left ventricular mass index compared to female sex (79.6 vs. 66.2 g/m2, p < 0.001) in Korean adults without prior cardiac disease.
Observational (n=172)
No
This study establishes sex-related normal reference values and percentiles for left ventricular functional parameters using 320-detector-row coronary CT angiography in Korean adults.
Provides sex-specific LV mass references for Korean adults; leaves open generalizability and outcome prediction.
OBJECTIVE: To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. MATERIALS AND METHODS: ) who underwent CCTA without any prior history of cardiac disease. The following parameters were measured by post-processing the CT data: LV volume, LV functional parameters (ejection fraction, stroke volume, cardiac output, etc.), LV myocardial mass, LV inner diameter, and LV myocardial thickness (including septal wall thickness [SWT], posterior wall thickness [PWT], and relative wall thickness [RWT = 2 × PWT / LV inner diameter]). All of the functional or volumetric parameters were normalized using the BSA. The general characteristics and co-morbidities for the enrolled subjects were recorded, and the correlations between these factors and the LV parameters were then evaluated. Most of the LV parameters were positively correlated with BSA, body weight, and total Agatston score. CONCLUSION: This study provides sex-related reference values and percentiles for LV on cardiac CT and should assist in interpreting results.
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Kang et al. (2017) conducted an observational in Healthy adults (no prior cardiac disease) (n=172). Male sex vs. Female sex was evaluated on Left ventricular mass index (LV MI) (p=<0.001). Male sex was associated with a significantly greater left ventricular mass index compared to female sex (79.6 vs. 66.2 g/m2, p < 0.001) in Korean adults without prior cardiac disease.
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