Why the study?
There is a need to know the indexed heart values of people in each geographic region, motivating the establishment of normal left ventricle reference values.
What are the normal reference values for left ventricular mass and volume by CCTA in Caucasian adults?
Cross-Sectional (n=310)
What are the normal reference values for left ventricular mass and volume by CCTA in Caucasian adults?
Absolute Event Rate: 76% vs 60%
p-value: p=<0.01
This study establishes normal reference values for left ventricular mass and volume by CCTA in a Caucasian population, highlighting significant gender differences in indexed left ventricular mass.
Objectives: There is a need to know the indexed heart values of people in each geographic region. The objective of this study is to establish normal reference values for the left ventricle. Material and Methods: Of the 450 caucasian adult patients who underwent coronary computed tomography angiography (CCTA) from June 2021 to March 2023, 310 meeting the appropriate criteria were selected for our retrospective study. The indication for CCTA triggered by a 384-detector retrospective electrocardiogram was screening for coronary artery disease (CAD) in people over 40 years of age. Patients with known CAD, heart failure, congenital heart disease, heart transplant, known allergies to X-ray contrast, or prior cardiac surgery were excluded from the study. We determined normal reference ranges for end-diastolic myocardial mass (EDMM), end-diastolic volume (EDV), and cursor volume (CV) using indexed body surface area (BSA). Results: BSA indexed values are EDMM = 76 and 60g/m 2 , EDV = 65 and 61 mL/m 2 , CV = 46 and 42 mL/m 2 , heat index = 178 and 160 cm, weight = 89 and 81 kg, age = 55 and 57 years, and heart rate = 60 and 63 for men and women, respectively; 95% confidence interval. Conclusion: All parameters were different between males and females. In this cross-sectional general population study, men had significantly more indexed left ventricular mass than women ( P < 0.01), with no significant differences between men and women in all other parameters ( P > 0.05). These values indicate ethnic diversity.
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Celenk et al. (2024) conducted a cross-sectional in Screening for coronary artery disease (n=310). Male sex vs. Female sex was evaluated on Indexed end-diastolic myocardial mass (EDMM) (p=<0.01).
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