July 27, 2011EP EuropaceOpen Access

Women, but not men, have prolonged QT interval if depressed after an acute coronary syndrome

View Full Paper

Ask AI

Bookmark

Why the study?

Are depressive symptoms associated with prolonged QT interval in patients with acute coronary syndrome?

Structured PICO

Are depressive symptoms associated with prolonged QT interval in patients with acute coronary syndrome?

Population

382 hospitalized patients with unstable angina or non-ST elevation myocardial infarction (243 men, 139 women) from two prospective observational studies. Excluded: QRS duration ≥120 ms and/or prescribed antidepressants.

Intervention

Depressive symptoms (Beck Depression Inventory score ≥10)

Comparator

No depressive symptoms (Beck Depression Inventory score <5)

Outcome

QT interval corrected by Fridericia's method (QTcF) on admission electrocardiogramsurrogate

Depressive symptoms are associated with prolonged QT interval in women, but not men, following an acute coronary syndrome, suggesting a gender-specific mechanism linking depression and abnormal cardiac repolarization.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Depressive symptoms linked to QT prolongation in women post-ACS; leaves open arrhythmic implications and needs prospective confirmation before guiding care.

Cite This Study

Whang et al. (2011) studied this question.

synapsesocial.com/papers/6a35db29e8fad655376e506a https://doi.org/10.1093/europace/eur246

View Full Paper

Ask AI

Bookmark

Implication

Depressive symptoms linked to QT prolongation in women post-ACS; leaves open arrhythmic implications and needs prospective confirmation before guiding care.

Women, but not men, have prolonged QT interval if depressed after an acute coronary syndrome

Structured PICO

Discussion

Implication

Cite This Study

Women, but not men, have prolonged QT interval if depressed after an acute coronary syndrome

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider